My '75 Fuji was originally a 10-speed (2x5) with the ubiquitous SunTour 14-28 out back and Sugino Maxy 51/39 crainrings. Over the years it has turned into an 18-spd (3x6). The crankset now is a Sakae SX 48/38/28 and it now wears a 13-26 6-spd Suntour Winner Ultra freewheel (just took off the 13-21 Ultra). Derailleurs are currently SunTour Compe-V front and a long cage MD(?) MTB rear (bought when my VGT-Luxe ate a pulley several years ago)... Never had a problem shifting at all. No really steep hills around here so the 28/26 is kinda overkill, but I want to try some loaded touring in the OH/PA/WV region.
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'75 Fuji S-10S bought new, 52k+ miles and still going!
'84 Univega Gran Tourismo
'84 Univega Viva Sport
'86 Miyata 710
'90 Schwinn Woodlands
Unknown brand MTB of questionable lineage aka 'Mutt Trail Bike'
Plus or minus a few others from time-to-time