Kind of yes, kind of no.

BB drop is inherent to a frames design, its the distance from the centerline of the axles down to the centerline of the BB. Its a fixed value for a given wheel position. I suppose if you have super old school angled 60's dropouts there may be a small measurable difference in BB drop when the wheel if shifted from extreme front to extreme rear. For more modern bikes with more flat drop outs and short dropouts on top of that its of no significance.

That being said, if you flip a bike upside down the drop becomes negative.