I rode 50 miles over the weekend with 44/18 gearing (66"). Finished in just under 3 hours, which is a normal time for me on a geared bike. I calculated average cadence in the high 80's, which means I must have spent a lot of time in the 100's. I don't know for sure, but I think that's a higher average cadence than I would have had on a geared bike. I like the gear everywhere but downhill where I feel out of control when my cadence gets above 120 or so, especially if the decent is bumpy.
I switched to a 44/17 (70") on Monday and did a couple of 25 mile rides this week. I like that gear better for the flat and much better downhill (my 17 tooth is a freewheel), but it's too big of a gear for me riding into a headwind.
I may try a 42/17 (67") or a 45/18 (68") to see how that works. For what it's worth, I think riding fixed is more interesting than SS.