The reason I ask is that when I got my Roubaix, it came with a 16 count, 2.0 mm spoke, radial laced wheel. I remember thinking it was kind of harsh. For other reasons I ended up on a 32 count, double butted 2.0/1.5mm spoke, 3 cross front wheel and I didn't notice at the time, but the harshness went away when I changed to that wheel. This week I had to return to the stock 16 spoke, radial laced front wheel to the bike for one ride and that harshness was back big time.
The forum experts say I'm crazy if I think I noticed a difference, but there was one. Just some anecdotal info to keep in mind as you make your decision.