The losses in the rohloff are way below 10 percent. And when I brought this issue up on another site, I was roundly savaged for my ignorance, there are at least some who believe these hubs are more efficient even with the titanic weight. It comes down to the fact that we readily accept the inefficiency of the derailleur, how dusty and dirty it gets, the angles, the longer chain, the weight in the cranks, and so forth. Then the issues of gear range come up, and the next thing you know someone is advocating a fixed drive, in San Francisco. I mean somewhere between that stage of your life, and the electric wheelchair, there might be a place for a few gears.
Anyway, I haven't used one, and the main advantages in durability really don't mean much to the real world of even my touring and MTBing to date. But it is certainly an interesting trend. The main thing the Nexus has going for it is that it has a full double range, and triples only really became the norm about 20 years ago, so we are at a reasonable place relative to gearing, and a reasonable price. I'm not plunking down what they want for a Rohloff until a few more decades have gone by. I have no interest in paying early adopter prices.
I also remember when bikes didn't have quick releases, in fact I'm getting them off my bikes. With the fenders all coming to the same point of attachment in the old days, we fixed almost all our tires in place, and kept them about 5-10 patches worth. With the new instant patches being so low profile a few patches seem reasonable. The way you find holes if it is noisy or whatever, is just use your eyes, and when you find something suspicious, put your finger over it with a little spit Don't worry your inertube is already wearing a rubber, you won't catch anything!