Armstrong was originally a bit stockier but had enough natural power & endurance to do very well at one-day & shorter stage races. Le Tour is crazy tough & it's fairly common for talented cyclists to still require years to excel there. I think Lance might have had some trouble cutting weight in transition from power rider to all-round GC contender.

W/O doping I'd guess he'd have at least later worked up to TDF GC top-ten.

BTW after NFL "Inflate-Gate" scandal I saw old star quarterback Fran Tarkenton being interviewed. He tried to steer conversation to rampant NFL doping (ie far more important than inflation nonsense) & the interviewer not the least bit interested. Bizarrely, pro wrasslin' seems to have really steered away from doping. In times past almost all the top guys did steroids but now many of them are far less muscled. Of course wrasslin' is fixed anyway.