I tried using creatine in the past and didn't see a benefit. However, this thread got me looking it up in WebMD, which says it is also used to treat certain conditions. One of the conditions listed is high cholesterol. Considering we've had a few threads on statins, that aspect might be of interest to more than just me. Creatine is naturally produced in the body... Hmm... maybe a clinical test of one would be in order?