My current bike has the first comfort saddle I've ridden. It gets noisier all the time. At first I mistook the squeaks for bottom bracket troubles, because the noise resonates oddly through the fat aluminum tubes. But it's just the saddle.

Only cure might be to disassemble it and wax the various plastic mating surfaces. Oil or grease might work for a few minutes before it attracted gritty debris. Not worth the effort. Eventually I'll replace the saddle, but there's really not much wrong with this one. I'll just keep riding and ignore the squeaks. Reminds me to focus on pedaling more smoothly, since it squeaks more when I bounce.