Originally Posted by Drew Eckhardt

Sometimes. Seat tube angles often flatten as the sizes grow.

With a 73cm saddle height there's 1.2cm more setback with the saddle rails in the same location moving from a smaller size with a 74 degree seat tube angle to a 73 degrees.

Sometimes not. The range of angles can be very small on the same frame model - 74 degrees through a 53, 73 through 59, 72.5 for a 61.

Look at the geometry charts and apply the necessary trigonometry.