I'm 70 and I've been riding an ISM Prologue on my Colnago for the past 3 1/2 years and at this point, I don't think I will ever ride on a different saddle, ever again. It was love at first sit and hasn't changed since then. I ride 8-10,000 miles a year and this saddle has never caused me any pain or discomfort whatsoever.
That said, I have suggested the ISM line of saddles to several of my friends only to find out that they are not for everyone. If you have wide sitbones, these saddles may not be what you are looking for. I would strongly recommend that you try one before you buy. Before you ride on one, make sure that you view the videos on their website for proper mounting of the saddle as they don't mount like standard style saddles do.
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HCFR Cycling Team
Ride Safe ... Ride Hard ... Ride Daily
2017 Colnago C-RS
2012 Colnago Ace
2010 Giant Cypress