It is likely that 135mm will eventually be adopted by road standards, but we're not there yet, and I wouldn't be too eager to jump ahead of the game. There are also reasons why the industry isn't eager to change.
Technically the current standard is the 131mm, but everyone seems to ignore that extra mm.
As far as cold setting or not, there are equally valid arguments either way. I run friction shifters on my old bike with 9 speed on the rear and vintage 5/6 speed on the front. So far I haven't cold set it, but run an off center rim instead. Since I have several bikes, there would be advantages to making everything match, but I prefer having one wheel set per bike anyway.