I'm not much of a slime fan, but there are some newer latex sealants that should be worth considering. Unfortunately with my first tubeless experiment (Schwalbe One Pro), I hit a rock wrong and tore a chunk out of the tire. And, unfortunately, it would seal with the hole in one place, but would leak out as soon as I started moving.
I do have a slow leak in one tire (with tube) now. Pumped it up twice, but time to hunt it down, probably one of those radial wires, and slime might have been enough for a permanent fix of that.
Schwalbe is experimenting with "self-sealing" tubes.
Schwalbe Protek Max Tubes.
I think they have a combination of slime inside, as well as a unique tube design that is supposed to help hold the holes closed (I've also discovered that using tubes rated for the tire size... say 25/35 tubes in 25mm tire, will help reduce the speed of leaks).
Anyway, I have my nephew testing some of those Protek tubes in goathead territory. I have high hopes for them, although patching could be a problem.