Originally Posted by
cxwrench
If the wheel is straight and centered it doesn't matter, it is what it is. If you add or remove tension it won't be centered.
It's not as simple as adding or removing tension. In order to keep tension fairly even while also truing the wheel, you can often choose to loosen one while tightening the next one over (from the same side) to achieve similar trueness. Whether that is the case for the OP in this situation is up for debate.