I did this a couple times as a quick way to lock the front wheel to the frame to supplement my other lock that was back on the rear wheel/frame. I used the Peerless handcuffs that I carry at work (I get to take them home). Handcuffs really aren't near as secure as people think. They're designed as temporary restraints only. For one thing, they use a universal key, and the links are quite tiny. They were designed for people, not things. That's why you always put the keyholes facing the subjects elbows when you cuff him; it's physically impossible to bend your wrists up around the backside of the lock to pick it. Very insecure for bikes though.

They look cool as hell though. Very satisfying clicking/ratcheting sound.