I re-built my '72 Fuji Finest to be more comfortable. I added Nitto Technomic stem from Rivendell and the Nitto Noodle bars. This allowed the handlebars to be higher than the seat which I changed to a Brooks B17. This made the Fuji more comfortable than the Specialized Sequoia, which is a comfort road bike. I had bought the Specialized for the gravel trails around here.
I think it is definitely worth a try on the Colnago.