Is it the front or rear wheel?
I would start by feeling/listening to the spokes as most time it is the spoke tension in the wheel that is off balance (the spokes are not saring the load properly).
All the spokes on the front wheel should feel and sound the same (equal tension on all spokes).
The drive (cassett) side of the rear wheel will feel stiffer (higher tension) and have a higher pitch (sound) the other side will have a softer feel and lower pitch (lower tension) for traditional rims (all the spoke holes in the middle of the rim) but for an OCR (off center rim) the tension should be similar to that of the front wheel.
Another problem could be spoke size vs the weight of rider but I'd take the wheel to a shop for that determination.