Originally Posted by kingsteve233

So if you get a flat and use a CO2 pump to re-fill.. you should empty and re-fill your tire with the floor pump back in the garage after making it home?

Does anyone put nitrogen in their road tires? Like at the tire shops now you can have them inflate your tires with the stuff for extra. That would be overkill for a bike. I'm still waiting for compressed helium to fill my tires with.

Originally Posted by Kotts

You got it right on the money. Molecular Nitrogen (which makes up the vast majority of plain 'ol air) is a much larger molecule than CO2, thus it's dang near impossible to compress a useful amount of it into an itty-bitty cylinder. This is also the problem with CO2, since it's a smaller molecule, it bleeds out through the rubber of an inner tube more easily.