how comfortable do you want to get?
whats your budget?
If you wanted super comfortability you could buy a gel seat, then put a gel seat covers over the seat itself.
For wrist comfortability you can get gel-inserted handlebars, then buy really thick cycling gloves.
those are your main 2 points of contact that associate with comfortability.
Although carbon fiber generally takes in more shock, generally it doesn't effect the heavier riders as much as the light weights (<150 lbs).