Microshift control levers are designed to be compatible with Shimano drivetrains, so their 10-speed levers will work with 10-speed 105, Ultegra, or Dura-Ace derailleurs and cassettes. That means you will need Shimano or Shimano-compatible derailleurs (Microshift), a Shimano-compatible 10-speed cassette hub, and a Shimano or Shimano-compatible (SRAM) cassette. Also, the distance between your frame dropouts will need to be stretched to 130mm (from 120 or 126.5).
I had the opportunity to test Microshift's 8-speed levers, with Sora, I believe. The lever throws were long, for shifting and braking, and the levers were too flexible. The 10-speed levers, reputedly co-developed with Eric Sampson, are supposed to work better. The ones in the photo look suspiciously like the 8-speed levers I tried. I'd rather use Microshift derailleurs with Shimano levers.
The Modolos might be worth a try if you or someone you know is good at setting up indexed shifters.
Last edited by oldbobcat; 03-09-09 at 10:19 AM.