I think there is a really good chance that 100 grams on each wheel is as significant as 10 pounds in the bags. Wheel weight is the biggest performance factor in your bike. That said wheel durability still can't be compromised.
The deep V rims are strong, but that kind of design is mostly needed when low spoke count wheels are used. With 36 or more spokes, rim cross section is not as critical to strength, and other factors that provide strength can be emphasized instead. Some of the classic strong wheels are fairly narrow in width and shallow in depth. The MA2 being the classic example. Velo Orange is introducing an MA2 clone, though how comparable it is remains to be seen.