I've been seeing a few saddles tilted in ways that look uncomfortable to me lately. Too far forward makes me feel like I'm sliding forward when my hands are off the bars and puts more pressure on my palm/wrist/ulnar nerve. Too far rearward and I feel like a HotDog-on-a-stick, so to speak.
Obviously riding style is going to play a part in this, but on your "pedaly" bike...how is your saddle tilted?
Show a pic if ya got it.